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ABOUT THE BOOK

This volume in the popular series, Drugs and the Pharmaceutical Sciences, begins with the history of cancer treatment, carcinogens, and molecular mechanisms involved in cancer pathogenesis. It incudes conventional and advanced cancer therapies ranging from oral and parenteral preparations to advanced fabricated systems such as nanoparticles, liposomes, antibodies, aptamers, poly(amidoamine) and photodynamic therapies. The preparation and mechanisms of molecular targeting of cancer are presented and the authors focus on a diverse audience including undergraduates and research students.

Features

• Timely coverage of changes in process control technology for the phamaceutical industry, a dynamic area in terms of products and manufacturing processes
• Provides an update on the unique requirements of these industries and how they differ from others, for example the microelectronics or specialized chemicals industries
• Draws on the author's vast experience in the field of industrial hygiene and hazardous materials
• Presents a collection of unique situations in which industrial hygiene was implemented to resolve a variety of scenarios and did not interfere with quality issues
• Addresses current topics relating to industry evolution such as migration of therapies to higher potency, RiskMAP, new modalities in medicines and treatments, large molecule therapeutics and conjugates.

TABLE OF CONTENTS

1. History of Cancer Therapies

Isma Iqbal, Daulat Haleem Khan, Maria Manan, Zainab Abdullah, , Muhammad Ali Syed, Sana Hanif, Zeliha Selamoglu, Muhammad Yasir Ali, Azhar Rasul

2. Cancer and Carcinogens

Saba Riaz, Azhar Rasul, Muhammad Asif Khalil, Laiba Ameen, Komal Riaz, Samreen Gul Khan, Sevki Adem, Mudassir Hassan, Muhammad Javid Iqbal, Muhammad Asrar, Muhammad Yasir Ali

3. Causes of Death from Cancer

Hafiz Muhammad Irfan, Muhammad Ihtisham Umar, Usman Sabir, Muhammad Yasir Ali, Ummaima Shahzad

4. Passive Targeting

Malik Saadullah, Amna Sehar, Khurram Afzal, Ijaz Ali, Shams ul Hassan, Muhammad Yasir Ali

5. Cancer Active Targeting Strategies

Tanzeela Awan, Ghazala Ambreen, Uzma Saher, Saira Afzal, Muhammad Yasir Ali, Asia Naz Awan

Conventional Cancer Therapies

6. Oral Anticancer Therapies

Ayesha Saeed, Liaqat Hussain, Hua Narenmandura, Qian Qian Wang, Muhammad Yasir Ali, Ummaima Shahzad, Ijaz Ali

7. Parenteral Anticancer Therapies

Mishal Fatima, Liaqat Hussain, Yasen Maimaitiyiming, Hua Naranmandura, Ayesha Saeed, Yang Chang, Muhammad Yasir Ali, Ummaima Shahzad

Advanced Cancer Therapies

8. The Advent of Micro and Nano-spheres for Cancer Treatment

Asia Naz Awan, Rabia Iqtadar, Sabahat Abdullah, Muhammad Yasir Ali, Imran Tariq

9. The Emergence of Liposomes in Cancer Therapy

Asia Naz Awan, Sabahat Abdullah, Ayesha Naseer, Muhammad Yasir Ali, Daulat Haleem Khan

10. Niosomes-Based Anticancer Therapies

Daulat Haleem Khan, Muhammad Yasir Ali, Muhammad Asim Farooq, Muhammad Ali Syed, Azhar Rasul, Shazia Anwar Bukhari, Sevki Adem, Maria Manan

11. Solid Lipid Nanoparticles-Based Anticancer Therapies

Mulazim Hussain Asim, Muhammad Yasir Ali, Shumaila Arshad, Ummaima Shahzad, Arshad Mahmood, Syed Atif Raza, Alia Erum, Ali Moghadam

12. Mesoporous Nanoparticles-Based Anticancer Therapies

Tanzeela Awan, Uzma Saher, Muhammad Yasir Ali Umair Amin, Sajid Ali

13. Antibody-Based Cancer Therapies

Malik Saadullah, Hafsa Tariq, Muhammad Yasir Ali, Saeed Ahmad, Nisar ur Rehman

14. Aptamer-Based Anticancer Therapies

Muhammad Yasir Ali, Ummaima Shahzad, Maryam Shabir, Nisar ur Rehman, Saeed Ahmad, Udo Bakowsky, Umair Amin, Imran Tariq, Ghazala Ambreen

15. Polyamidoamines-Based Anticancer Therapies

Maria Manan, Rida Siddique, Maryam Shabir, Azhar Rasul, Nosheen Aslam, Uzma Saleem, Muhammad Yasir Ali, Shazia Anwer Bukhari, Mulazim Hussain Asim

16. Photodynamic Therapies for Cancer Treatment

Ayesha Sadiqa, Saba Riaz, Azhar Rasul, Rabia Zara, Khudeja Afroz, Zunaira Saeed, Gul Bushra Khan, Khatereh Khorsandi, Muhammad Yasir Ali